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Symbol
Name
ID
Pdpk1
3-phosphoinositide dependent protein kinase 1
MGI:1338068
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations

Mouse Phenotypes
increased pituitary gland apoptosis
increased corticotroph apoptosis
increased melanotroph apoptosis
decreased adrenal gland zona fasciculata size
abnormal pancreatic beta cell morphology
pancreatic islet hyperplasia
small pancreatic islets
pancreatic islet hypoplasia
decreased corticotroph cell number
abnormal pituitary intermediate lobe morphology
abnormal melanotroph morphology
small pancreas
small testis
decreased insulin secretion
abnormal pancreas physiology
Availability Mouse Genotype
Pdpk1tm1Dral/Pdpk1tm1Dral
Pdpk1tm1Jcbr/Pdpk1tm1Jcbr
Tg(Pomc1-cre)16Lowl/0  (conditional)
Pdpk1tm1Maka/Pdpk1tm1Maka
Tg(Ins2-cre)23Herr/0  (conditional)
Pdpk1tm1Maka/Pdpk1tm1Maka
Tg(CAG-cat,-lacZ)11Miya/0
Tg(Pomc1-cre)16Lowl/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory